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Claudius D'Silva

Chemistry & Environmental Science
Manchester Metropolitan University

Interests

Soft Functional Materials, Biopolymers, macrocycles, Sensors, sustainable energy, chemical biology

Publications

Cau� P. Pascholati, Esteban Parra Lopera, Felippe J. Pavinatto, Luciano Caseli, Thatyane M. Nobre, Maria E.D. Zaniquelli, Tapani Viitala, Claudius D\'Silva, Osvaldo N. Oliveira Jr. Colloids and Surfaces B: Biointerfaces, (2009), The Interaction of an Antiparasitic peptide\n
Active against African Sleeping Sickness with Cell Membrane Models. 74(2) 504-510.\n
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Fotea, C. & D�Silva, C & Spear, S., (2007) Waterproofness results for the surface treatment of heavy-duty leather for adhesion enhancement. J.Adhesion. 83, 813-819.\n
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Fotea, C. & D�Silva, C., (2005) The enhancement of adhesion to chromium tanned heavy-duty leather (Salz leather) under extreme conditions using photoreagents as surface primers. Int. J. Adhesion Adhesives. 25, 442-449.\n
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Fotea, C. & D�Silva, C., (2004) A comparative study on the use of photoreagents for the enhancement of adhesion on heavy-duty leather (Salz leather). Int. J. Adhesion Adhesives. 24, 479-484. \n
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Fotea, C. & D�Silva, C., (2004) The use of silane reagents as primers to enhance the adhesion of Cr tanned leather surfaces. Int. J. Adhesion Adhesives. 24, 1-7.\n
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Daunes, S., D\'Silva, C., (2002) Glutathione Derivatives Active against T.b.Rhodensiense & T.b.Brucei in vitro. Antimicrob. Agents Chemother. 46, 434-437. \n
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D�Silva, C, & Daunes, S (2001) A prodrug approach to glutathione derivatives with in vitro antiparasitic activity. Amino Acids, 21, p87. \n
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Daunes, S., D\'Silva, C., Kendrick.,H, Yardley, V., Croft, S. L., (2001) A QSAR Study on the Contribution of Log P and Es to the in vitro Antiprotozoal Activity of Glutathione Derivatives J. Med. Chem, 44, 2976-2983.\n
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D\'Silva, C., Daunes, S., Rock, P., Yardley, V., Croft, S. L., (2000) A Structure Activity Study on the Antiprotozoal Activity of Glutathione Derivatives J. Med. Chem., 43 (10), 2072-2078.\n
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D\'Silva, C., (1999) The Transduction of Molecular Recognition Information into Electronic Signals. Materials Engineering Society of the School of Technology Tunku Abdul Rahman College, 19th Volume, 1999, Issn-0127-4759.\n
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D�Silva, C., Walker, D.,(1998) Acid-base Catalysis in the synthesis of Arylmethylene and arylalkyl methine pyrroles. J.Org.Chem. 63, 6715-6718.\n
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Cathala, B., Picard, C., Cazaux, L., Tisnes, P and D\'Silva. C. (1996) Bibracchial Diazatetralactams. II. Side Arm Effects on Cation Binding and Ionophoric Properties. Perkin II, 4, 685-689.\n
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D\'Silva. C., Iqbal. R., (1996) A New method to N-Alkyl & Aryl pyrroles, Synthesis, 4, 457-458.\n
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Williams, G., and D\'Silva, C., (1996) A Photo-encapsulation technique for micro-fabricated electrodes, Sensors & Actuators. B, 30, 151-157\n
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Farrell, C., Rowell, F. J., Cumming, R. H. and D\'Silva, C., (1994)., Enzyme-linked Immunosorbent Assay for Ceftazidime in Airborne Samples., Analyst., 119., 2411-2316.\n
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Cazaux, L., Tisnes, P., Picard, C., D\'Silva, C & Williams, G.,(1994) Macrocyclic Polyether Tetralactams IV. A Potentiometric evaluation of the Ion-Selective Characteristics with Alkaline-Earth Cations., Analyst., 119., 2315-2318.\n
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Williams, G., and D\'Silva, C., (1994) A Field Based Heavy Metal Analyser for the simultaneous determination of multiple cations on-site. Analyst., 119., 2337-2342.\n
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Moriarty, R. M., Roa, M. S and Tuladhar, S. M., (USA); Williams, G. and D\'Silva, C. (1994) Comparative Evaluation of the Ion-Selective Characteristics of 1,4-bridged Cubane Diester Crown Ethers. J. Phys. Org. Chem ., 7, 303-308.\n
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Williams, G., and D\'Silva, C., (1994) Hand-held Instrumentation for Enivironmental Monitoring Analyst. 119, 187-191.\n
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Williams, G., and D\'Silva, C., (1993). A General Sensor Interface Chip (GSIC) for use in Chemical and Biochemical Sensors., Sensors VI. Technology, Systems & Applications., eds. Grattan, K. T. V., Augousti, A. T., Institute of Physics Publishing, UK. 161-166 (1993).\n
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Morgan, H., Taylor, D. M., Fukushima, H. and D\'Silva, C. (1993) Self-Assembly of Streptavidin/BisBiotin Monolayers and Multilayers. Molecular Crystals and Liquid Crystals., 235, 121-126 .\n
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Moriarty, R. M., Roa, M. S. C., Tuladhar, S. M., (USA); D\'Silva, C, Williams, G. and Gillard, R. (1993) Crown Ether Ionophores. Construction of Neutral Ion Selective Electrodes. J. Am. Chem. Soc. 115 (4), 1194-1196.\n
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D\'Silva, C., (1992) Molecular Recognition: A Route to the Self-Assembly of Molecular Circuitry., Ann. Inter. Conf. of IEEE EMBS, 14, 191-193. \n
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Williams, G., Tuladhar, S. and D\'Silva, C., (1992) Potentiometric Evaluation of 2-Borono-1,3-Xylyl macrocycles as Ion selective electrodes .J. Phys. Org. Chem., 5, 437-442. \n
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Aferworki, S., Baker, P., Parri, O. L, and D\'Silva, C (1992) The Synthesis and Polymerisation of 1,1\'-substituted vinylferrocenes of the type [Fe(n5- C5H4X) (n5-C5H4 (CH=CH2)] (X= Cl, Br, CN or CONH2). J. Organometallic Chemistry., 431, 81-86.\n
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Barnes, C., D\'Silva. C., Jones, J.P., Lewis, T.J. (1992) Lectin Coated Piezoelectric crystal Biosensors, Sensors & Actuators B, 7, 347-350 .\n
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Barnes, C., D\'Silva. C., Jones, J.P., Lewis, T.J. (1992) The Theory of operation of Piezoelectric Crystal Sensors for Biochemical Applications, Sensors & Actuators A, 31, 159-163.\n
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Morgan, H., Taylor, D. M., D\'Silva, C. and Fukushima, H. (1992) Self-Assembly of Streptavidin/BisBiotin Monolayers and Multilayers. Thin. Film & Solids. 210-211, 773-775.\n
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Morgan, H., Taylor, D. M and D\'Silva, C., (1992) Surface Plasmon Resonance Studies of Chemisorbed Biotin-streptavidin Multilayers. Thin. Film. Solids 209. 122-126.\n
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Tuladhar, S and D\'Silva, C., (1992) Synthesis of Poly-N,N\'-Dimethylethylene diamines, Tetrahedron Letts 33, 2203-2206.\n
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D\'Silva, C., Aferwoki, S, Parri, O. L., Baker, P. and Underhill, A . (1992) Electrochemical Characterisation of Polyvinylferrocene polymers. Substituent Effects on the Redox reaction. J.C.S. J, Mat. Chem . 2 , 225-230.\n
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Tuladhar, S and D\'Silva, C., (1992) Synthesis of 2-Borono-1,3-xylyl Macrocycles. Tetrahedron Letts. 33, 263-268.\n
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Barnes, C., D\'Silva. C., Jones, J.P., Lewis, T.J. (1991) A Concanavilin A Coated Piezoelectric Crystal Biosensor., Sensors and Actuators B, 3, 295-304.\n
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Tuladhar, S., Williams, G., and D\'Silva, C., (1991) Comparitive studies on 1,3 Xylyl and 2 -Bromo 1,3 Xylyl crown ethers as ion selective electrodes. Anal Chem, 63, 2282-2285 .\n
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Taylor, M, Morgan, H., D\'Silva. C., (1991) Characterisation of Chemisorbed Monolayers by Surface Potential Measurements., J. Phys. D. 24, 1443-1450.\n
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D\'Silva, C., (1991) The use of Glutathione Analogues as Probes to the Active -Site of glutathione dependent enzymes. Amino Acids, 1. 114. \n
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Taylor, M., Morgan, H., and D\"Silva, C. (1991) Assembling Networks for Molecular Electronics. Mackromol Chem., Mackromol Symp. 46, 1-8.\n
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Taylor, M., Morgan, H., D\'Silva. C. (1991) Behaviour of Avidin and Avidin /\n
BisBiotin Polymers at the Air-water Interface. J. Colloid and Interface. Sci., 144, 53-62.\n
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D\'Silva, C & Green, D. (1991) Cooperative Binding of Polyols by Phenylboronic acids J. Chem. Soc. Chem Commun. 227-229.\n
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D\'Silva C. (1990) Synthesis of carboxyl modified coenzyme derivatives as probes to the mechanism of glutathione dependent enzymes. Biochem. J. 271, 167-169.\n
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D\'Silva C. (1990) Inhibition and Recognition Studies on the glutathione\n
binding site of Equine liver glutathione-S-transferase. Biochem. J. 271 , 161-165.\n
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Wang, Xiao-Bo, D\'Silva, C and Pethig R. (1990) Electronic Charge Transfer\n
Characterisation of Redox Polymer films using Normal Pulse Voltammetry. J. Mol. Elect. 6, 129-139.\n
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D\'Silva C., Wang, Xiao-Bo. and Pethig R. (1989) Physical and Electrochemical Characterisation of Polyvinylferrocene Films. J. Phys. D. 22, 1591-1597.\n
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D\'Silva C., Williams C.H. Jr. and Massey V. (1987) Identification of methionine-110 as the residue covalently modified in the electrophillic inactivation of D-amino acid oxidase by O-(2,4-Dinitrophenyl)hydroxylamine. Biochemistry. 26, 1717-1722.\n
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D\'Silva C., Williams C. H. Jr. and Massey V. (1986). Electrophillic Amination of a single Methionine residue located at the active site of D-amino acid oxidase by O-(2, 4-Dinitrophenyl)hydroxylamine.Biochemistry. 25, 5602-5608.\n
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D\'Silva C. (1986). Reinvestigation of the roles of the carboxyl groups of glutathione with yeast glyoxalase I: Implications to the mechanism and coenzymic role of glutathione. FEBS Lett. 202, 240-244.\n
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D\'Silva C. and Douglas K.T. (1983). Light sensitivity of Chromomycin A3 and of its Magnesium (2+) complex . IRCS. Med. Sci. 11, 294-295.\n
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D\'Silva C. and Douglas (1983). Photoaffinity labelling of yeast glutathione reductase by a bifunctional aryl azide derivative of oxidised glutathione . Photobiochem. and Photobiophys. 5, 151-158.\n
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D\'Silva C and Douglas K.T. (1983). Electrochemical preparation of catechol dipeptides as metal chelators and enzyme inhibitors. J. Org. Chem. 48, 263-265.\n
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Gray C.J., D\'Silva C., Boukervalis J. and Barker S. A. (1983). 4-Methylumbelliferyl esters as fluorogenic substrates for proteases. Enzyme and Microbial Tech. 5, 137-142.\n
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D\'Silva C., Timari A.A. and Douglas K.T. (1982). Synthesis of N-acyl glutathione derivatives by dimethylaminopyridine catalysis. Biochem. J. 207, 329-332.\n
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Douglas K. T., Timari A.A., D\'Silva C. and Gohel D.I. (1982). Role of the N-terminus of glutathione in the action of yeast glyoxalase I. Biochem . J. 207, 323-329.\n
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Gray C. J., D\'Silva C. and Barker S.A. (1982). Yeast aspartate aminotransferase. Preparation of the apoenzyme and coenzyme analogues and their interaction with enzyme. Enzyme and Microbial Tech . 4, 419-425.\n
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Hoog J. O., Douglas K.T., D\'Silva C. and Holmgren A. (1982). Photoaffinity labelling of glutaredoxin from Escherischia Coli. Biochem. Biophys. Res . Commun. 107, 1475-1481.\n
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Hoog. J. O., Holmgren A., D\'Silva C., Douglas K.T. and Seddon A.P. (1982). Glutathione derivatives as inhibitors of ribonuclease reductase from E. coli. FEBS Letts. 138, 59-61.\n
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Douglas K.T., Seddon A.P., D\'Silva C. and Bunni M. (1982). Photaffinity labels for glutathione and glutathione disulphide utilising systems. Trans Biochem Soc. 10, 124-125.\n
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D\'Silva, C., Seddon A. P. and Douglas K. T. (1981). Photoaffinity labels for enzymes capable of binding glutathione or its disulphide. JCS Perkin I 12, 3029-3033.\n
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REVIEWS/BOOKS\n
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D�Silva , C, (2007), Human African Trypanosomiasis: Future prospects for Chemotherapy. Drugs of the Future. 32 (2), 149-160.\n
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D\'Silva, C., Daunes, S., (2002). The Therapeutic Potential of Inhibitors of the Trypanothione Cycle. Expert Opinions in Drug Discovery. 11(2), 217-231. .\n
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D\'Silva, C., (1995) Receptor Based Biosensors., in Biosensors Vol 5 (Current Topics in Biophysics) ed: Petre T. Frangopol & Mircea Sanduloviciu, Iasy University Press, Iasy, Romania. pg 1-19.\n
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Barnes, C., D\'Silva. C., Jones, J.P., Lewis, T.J. (1992), The Theory of operation of Piezoelectric quartz crystal sensors for biochemical applications , Proceedings of Eurosensors V, Vol 2, pg 159-163, A. D\'Amico, Elsevier, Amsterdam\n
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Barnes, C., D\'Silva. C., Jones, J.P., Lewis, T.
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Grade: Member

Member since May 12, 2011
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