The Collaborative Center for Translational Mass Spectrometry (CCTMS, Pirrotte Lab) is a next generation proteomics and metabolomics research center situated at the Translational Genomics Research Institute in Phoenix, AZ. The CCTMS develops and performs mass spectrometry analysis tailored for translational and clinical research, with a strong focus in cancer biology and precision medicine. The CCTMS is led by Dr. Patrick Pirrotte, Director of the center, and co-Director of Mass Spectrometry and Proteomics Facility at City of Hope's Comprehensive Cancer Center in Duarte, CA.
Key interests of the CCTMS/Pirrotte lab are to functionally map kinome-substrate interactions (phosphorylations) to map key signaling pathways in cancer and support the development of novel targeted therapies. The CCTMS has developed extensive bioinformatics pipeline provides data integration across proteomics, metabolomics, genomics and transcriptomics to provide a united and actionable overview of tumor biology in precision medicine clinical trials. The CCTMS is also hosting a number of research programs in ovarian cancer and medulloblastoma.
Brief Posting Description
A Research Associate position is available within TGen's Collaborative Center for Translational Mass Spectrometry. The purpose of this position is to perform all duties related to experimental design and execution, data analysis, general laboratory management responsibilities, and assisting/mentoring colleagues and/or interns.
Detailed Description
The candidate should be able to independently run systematic studies once properly trained. The candidate will be responsible for planning, execution, quality control, data analysis and communication with other groups. The candidate will be expected to work effectively with an interdisciplinary team of researchers, be self-motivated, have excellent organizational and communication skills, and able to multitask. The candidate is expected to collaborate in the preparation and presentation of grants, manuscripts, posters, and reports.
Under supervision, the candidate will:
Develop and optimize sample preparation and automation procedures, Operate and maintain nano-LC equipment and mass spectrometers, and troubleshoot LC-MS/MS experiments, Develop Good Laboratory Practice protocols, Work collaboratively with TGen scientists and collaborators to ensure timely analysis and reporting of research results, Keep detailed logs of experiments and report scientific findings through write-ups, presentations, posters, and manuscripts, Mentor students . Requirements:
An eligible candidate will minimally have a Bachelor's degree in a science-related field with 3+ years of experience (Cancer Biology, Molecular & Cellular Biology, preferably Proteomics).
Ideally, we are looking for 2+ years of experience
Thorough knowledge of Microsoft Office (Word, Excel, and PowerPoint) and any imaging software packages used to prepare figures for publication.
Ability to summarize techniques and findings in written form (publication quality)
Prior experience in the following fields are considered differentiating factors:
Molecular Biology Cancer Biology Proteomics and/or Metabolomics sample preparation High Performance Liquid Chromatography Mass Spectrometry Cell culture