Scientist, Bioscience Oncology

Scientist, Bioscience Oncology

Location – Waltham, Massachusetts (Boston)

Do you have expertise in, and passion for oncology research? Would you like to apply your expertise to impact drug development in a company that follows the science and turns ideas into life changing medicines? Then employment at AstraZeneca might be the right choice for you!

What is Happening at AstraZeneca

At AstraZeneca, we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We’re passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life.

This Opportunity

We are seeking a highly motivated Scientist in Targeted Tumor Delivery with deep scientific and technical expertise in antibody/antibody-drug conjugate therapeutics with a track record of scientific excellence to join our team in Waltham, MA USA. As a Scientist in our Oncology R&D department you will be a key member of a team focused on supporting oncology projects through the drug discovery and development process. You will bring your theoretical and practical expertise in cancer biology to establish assay systems and deliver datasets that will have direct impact on targeted therapeutics.

Oncology Vision

AstraZeneca’s vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death. A broad pipeline of next-generation medicines is focused on bringing novel concepts in immuno-oncology to unmet medical need.

Site Description

Our Waltham, MA facility builds life-changing medicines for people around the world. The modern, vibrant scientific campus employs more than 800 experts in our field, and it is only a short drive from Boston, MA. It is filled with cutting edge technology. Our work areas were built to facilitate teamwork, interaction and cross functional science. We believe employees benefit from being challenged and inspired at work.

The Boston R&D site located in Waltham, MA is situated within a biopharma cluster of academic research institutions, medical centers, pharmaceutical companies and biotech startups. The Boston region is consistently ranked #1 globally for biotech research, investment, talent recruitment and lab space. Site amenities include:

Modern 64-acre campus nestled in 200+ acres of nature conservation land & hiking trails

Flexible, agile lab design with co-located write-up space

Vibrant site community with activities, clubs, sports & games

Onsite business & meeting center, office, AV & catering support

Onsite outdoor activities (e.g. frisbee golf, garden club, volleyball, etc.)

The campus, also known as the Boston BioHub, is one of the largest and most dynamic life-science research hubs in the region. It’s home to more than 800 scientists and experts working in nine different pharmaceutical and biotech companies. The site is also home to the AstraZeneca Incubator, a program that helps emerging companies advance novel and innovative healthcare solutions to meet the needs of patients.

It is a great place to work in the heart of one of the world’s most vibrant research cities.

You will work in a laboratory within the Oncology Research group designing, conducting and analyzing in vitro and in vivo experiments to assess the function of our candidate oncology drugs and dissect the mechanism of action of novel therapeutics. You will also review emerging literature and internal data to identify new targets and contribute to target validation activities.

Bachelor’s or advanced degree in tumor biology or a related field

Depth of understanding for hematology cancer models as well as solid tumor models

Experience with a range of in vitro skills for the analysis of human tumor cell function (e.g. cell culture, cell signaling bioassays, high-content imaging, and cell death measurement in primary and cell line cultures)

Experience conducting multi-spectral flow cytometry and visualizing/quantitating high content multi-parameter flow data

Molecular biology skills including assessment of intracellular signaling and generation of engineered cell lines, generating and/or analyzing transcriptomic data

Strong interpersonal and collaboration skills together with evidence of having used these to support problem solving and delivery in a collaborative environment.

Experience in the evaluation of immune function and in the application of complex immunological assays

Experience working with cell death modulating agents, with biologics including antibodies and antibody-drug conjugates and evaluation of transcriptomic datasets

Familiarity with nano-medicine drug delivery

Knowledge of the drug discovery process and publications in credible scientific journals

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. We foster an inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you!

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

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