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Postdoctoral Associate | 3D Chromatin Genomics Lab

Postdoctoral Associate
Dr. Chia-Lin Wei, Principal Investigator

The 3D Chromatin Genomics Lab at JAX-GM is seeking to appoint a postdoctoral associate to participate in research directed toward elucidating the structures and dynamics of complex genomes. For more on the Wei Lab’s research and goals, visit: https://www.jax.org/research-and-faculty/faculty/chia-lin-wei

Postdoctoral Positions in Three-dimensional (3D) Chromatin Genomics
‪‪Chromatin interactions and its 3D structure play a major role in regulating gene expression by bringing together regulatory elements that are distal on the linear genome in close physical proximity with each other. Our Lab have pioneered genomic technologies for genome-wide profiling chromatin interactions. We are seeking enthusiastic, highly skilled computational and experimental post-docs to generate and analyze human chromatin interaction datasets in integration with other genomics and genetics datasets.‬ ‬‬‬‬‬‬‬‬‬
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‪We are seeking postdoctoral researchers to develop computational and genomic approaches for understanding 3D genome biology under the light of diverse genomic and genetic information. We are seeking self-motivated, independent individuals who are interested in building their own career paths; however, postdoctoral fellows are expected to coordinate with and report to the PI responsible for the research area(s) addressed by their project. The fellows will develop research projects in one or more areas of focus: ‬‬‬‬‬‬‬‬‬
3D genome mapping and imaging technologies‬‬‬‬‬‬‬‬‬‬‬‬Application of nano-engineering toward genomic methodologiesComputational modeling of 3D genome architecturesBuilding regulatory networks at multiple layers including gene expression, epigenetic, and chromatin dataIntegrating regulatory interactions with genetic dataMining and aligning chromatin interaction datasets in diverse human cell typesFunctional perturbation of topological elements Our Postdoctoral Associates enjoy distinct advantages, including:Advanced research in 3D epigenome technology and Biology.A uniquely collaborative environment that fosters interdisciplinary “team science” without departmental barriersUnparalleled genomic resources and superior research support servicesClose interaction with our award-winning faculty membersPartnerships with leading universities and medical centersNumerous courses and conferences focused on genetics, genomics and biomedicineExceptional benefits, ample time off and other valuable programsWorking for an institution that has repeatedly been voted among the top 15 “Best Places to work in Academia” in the world by readers of The Scientist
QUALIFICATIONS
PhD (or nearing completion of PhD degree)Background in human genetics or genomics and disease researchPublications (1st author highly advantageous) For computational postdocs desired attributes include:
Strong problem-solving skills, creative thinking, and enthusiastic about scienceExcellent communication skills and fully fluent spoken and written EnglishFamiliarity with next generation sequencing data sets and pre-processingExcellent programming skills,Familiarity with network building, mining, alignment algorithmsFamiliarity with bioinformatics resources, i.e., UCSC genome browser, NCBI. For experimental postdocs desired attributes include:
Strong problem-solving skills, creative thinking, and enthusiastic about scienceExcellent communication skills and fully fluent spoken and written EnglishFamiliarity with next generation sequencing data sets and data generationPhD in a genomics/genetics/biology or another relevant fieldExpertise in cellular and molecular biology techniques
About JAX: The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine! EEO Statement: The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
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