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Research Technician-Shih Lab

Job ID: 25778
Location: 450 Brookline Ave, Boston, MA 02215
Category: Research Technician/Scientist
Employment Type: Full time
Work Location: PTL Remote: 2-3 days remote/wk

Overview


An immediate opening for a research technician is available in Dr. William Shih’s lab. We aim to develop structural DNA nanostructure-based cancer immunotherapies. Successful candidates will work with an interdisciplinary team of scientists experienced in biochemistry, DNA nanotechnology, cancer immunotherapy, cellular and molecular biology and animal tumor models to develop novel cancer vaccines targeting a broad range of cancer types. The successful candidate will participate and learn the process of an interdisciplinary project using multiple technologies. This project is highly clinically translational.
We are seeking an enthusiastic and self-motivated candidate with cellular biology and/or biochemistry training who is willing to learn multi-discipline approaches for cancer immunotherapies. In general, the individual will work closely with a postdoc in charging of this project and be engaged in experiments that utilize biochemistry for DNA nanotechnology and immunological cellular biology techniques as well as animal tumor models after well-training. The individual will also assist in daily laboratory operations and organization. We are looking for candidates with a minimum of two-year availability. Candidates with laboratory technician experience and those potentially interested in a long-term position are encouraged to apply.



Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


Requirements


Conduct bench level experiments to support the goals of scientific research in DNA origami vaccine developmentExecute protocols to fold DNA origami and prepare vaccines; work with tumor cell, dendritic cell and T cell cultures, and cell stimulation and samplingAssist with experiments such as flow cytometry, ELISA, Western blots, and immunoprecipitation; assist with animal tumor model set up, observation and samplingOperate and maintain laboratory equipment (Such as microscope, TEM and flow cytometer) to complete investigationsMaintaining accurate records, analyzing data, writing reports, and preparing presentations; participate in team meetings for experimental planningPrepare, order, and maintain stocks of necessary reagents, solutions and supplies; organize lab items and maintain lab protocols up to date

Qualifications


Bachelor’s/Master’s degree in Biology or biochemistry related field required, or equivalent combination of education and experienceFamiliarity with basic laboratory techniques and principles of cellular and molecular biologySome knowledge in nanotechnology or immunology would be a plusMust feel comfortable working with miceEnthusiastic, team player, and self-motivated individual; excellent written and oral communication skills; knowledge of basic computer skillsStrong organizational skills, including the ability to handle a variety of tasks in a fast-paced environment required; Must have attention to detail and be thorough in completing work tasks.Cover letter is required, and three references should be provided

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.



Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.


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