Position Description:
The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.
Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.
PROGRAM DESCRIPTION
The Biopharmaceutical Development Program (BDP) of Leidos Biomedical Research, Inc. supports the Frederick National Laboratory for Cancer Research (FNLCR) and other government agencies through the development of novel agents for first-in-man clinical studies.
KEY ROLES/RESPONSIBILITIES
Both Levels require:
Development Associates will have the opportunity to do the following:
Design, optimize, and characterize upstream and downstream processes for the manufacture of biopharmaceuticals (monoclonal antibodies and therapeutic proteins) in early stage clinical development
Interpret analytical and process data and understand process implications
Maintain accurate records of experimental results, review, analysis and interpretations of experimental data
Make periodic presentations in group meetings, project team meetings, and in one-on-one situations
Prepare technical reports
Support technology transfer to in-house clinical manufacturing group
Evaluate new technologies to facilitate process development
In addition level IV requires:
Make periodic presentations in group meetings, project team meetings, and in one-on-one situations
Prepare technical reports
Support technology transfer to in-house clinical manufacturing group
Evaluate new technologies to facilitate process development
Proficiency in Fermentation and protein purification
Experience in process scale-up and technology transfer
Qualifications:
BASIC QUALIFICATIONS
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
This position may be filled with a Process Development Associate III/IV commensurate with the selected candidates experience.
Possession of Bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency
Basic knowledge of various aseptic techniques and working in a Biosafety Cabinet
Basic analytical techniques for protein products (HPLC analysis, protein quantification methods like gel electrophoresis; ELISA etc.
Familiarity with AKTA systems/software
Experience/knowledge with Microsoft Office software
Excellent written and verbal communication skills
Ability to obtain and maintain a clearance
Level III - In addition to the education requirement, a minimum of five (5) years of progressively responsible experience
Level IV - In addition to the education requirement, a minimum of eight (8) years of progressively responsible experience
In addition level IV requires:
Experience running Bioreactors 5 – 30L scale (Bacterial and cell culture)
Experience with large volume harvesting and homogenization
Experience with Filtration and TFF
To Apply:
For more information and to apply for the available position, please visit this website.
Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)