The Proteomics Resource Center at The Rockefeller University masters most aspects of mass spectrometry based proteomics which includes, denovo sequencing, targeted studies, quantitative proteomics profiling based on label free quantitation as well as metabolic labelled samples (SILAC), chemical labeling, tandem-mass tag technology, absolute quantitation and global post translational analysis. The Center also offers LC-MS based analysis of small molecules, polar metabolites and lipids. Very importantly, the Center is a source for help with planning of mass spectrometry based experiments and the Center have the capability to offer in-depth collaborative analysis. Also, the PRC is operated in a boutique style; encouraging the scientists of the Center to work closely with users to create a tailored approach to fit the many unique questions that can be answered by analytical mass spectrometry.
The PRC are equipped with Orbitrap type mass spectrometers (high resolution/high mass accuracy), operates a triple quadrupole and can separate analytes using both nano and high flow liquid chromatography. The Center is equipped with multiple high performance servers for data analysis.
In addition to analysis by mass spectrometry, the Center offers production of custom peptides and peptide libraries and different pre-mass spectrometry fractionation techniques, which include off-line separation of peptides and proteins by liquid chromatography.
Detailed Description
The Research Support Associate will apply mass spectrometry-based analytical chemistry to exciting projects, spanning a wide range of samples and project types. Reporting to the Director of the PRC, responsibilities include maintaining and operating nano and high-flow LC coupled to Orbitrap mass spectrometers and related equipment, interacting with and advising investigators about experiments, developing and implementing protocols in the Center, processing, analyzing, and interpreting data and reporting findings to investigators and the Director, tracking and submitting billing and purchasing information, and monitoring and maintaining laboratory appearance.
Job Requirements
Bachelor's degree required; educational emphasis in science-related fields, biology and chemistry preferred. Must have strong analytical and practical skills in sample preparation and data analysis and interpretation, excellent communication skills in oral and written English, the ability to work independently as well as part of a team, and flexibility to interact with a diverse group of researchers. Hands-on experience with liquid chromatography and mass spectrometry required. Must have experience in documenting experiments and maintaining and expanding knowledge of mass spectrometry techniques through self-education, dialog with experts, reading literature, and attending conferences and courses as necessary. Practical experience with informatics is desirable.
Additional Details
This job requires that employees be fully vaccinated against COVID-19 as a condition of employment. Rockefeller University provides reasonable accommodations where legally required including accommodations for medical conditions and sincerely held religious beliefs.