AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
The DMPK-BA department at AbbVie is seeking a highly motivated scientist to join the LC-MS Biomarker group. The main function of this position will be to drive the development, validation, and implementation of fit-for-purpose LC-MS methods for biomarker bioanalysis.
Key Responsibilities Include:
Develop methods, write validation plans catered to the intended use of the assays, conduct the validation runs, write validation reports, and conduct sample analysis, both non-clinical and clinical where appropriate (non-GLP, exploratory biomarkers), as well as publication of manuscripts for novel methods/analytical improvements. Depending on the target analyte and the intended use of the assay, various LC-MS configurations will be used, including analytical, micro, and nano LC as well as unit resolution and high-resolution MS. Identify and troubleshooting instrument and assay problems. Investigate, evaluate, and implement new methodologies, platforms, and technologies to meet challenging assay requirements while maintaining effective resource utilization. Act as the project leader on multiple projects, interacting with collaborators and internal project teams to understand study impact, define project needs and priorities, and present study outcomes. Mentor junior scientists.
Qualifications
Qualifications:
PhD (3+ years), M.S. (10+ years), or B.S. (13+ years) in analytical chemistry or biomedical sciences. Less industry experience (e.g., PhD 0-3 years) will be considered for a corresponding grade level. Fluent in the use of triple quadrupoles or other MS instruments as well as multiple flow rates/LC approaches. As a large portion of the work is expected to be on protein analytes, a strong background in protein LC/MS out of biological matrices (e.g., cells, tissues, fluids) is preferred, and experience in quantifying post-translational modifications is strongly preferred. Proven ability to work in a team environment and an ability to collaborate successfully across other groups within R&D. Working experience of regulated bioanalysis will be a plus. Strong communication and presentation skills.
Key Leadership Competencies:
Builds strong relationships with peers and cross functionally with partners outside of the immediate team to enable higher performance Learns fast, grasps the “essence” and can change course quickly when needed Raises the bar and is never satisfied with the status quo Creates a learning environment, open to suggestions and experiments to drive the science in the field of interest Embraces the ideas of others, nurtures innovation and manages innovation to reality Highly motivated and self-driven with the flexibility to quickly adapt to different projects.
Significant Work Activities
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel
Yes, 5 % of the Time
Job Type
Experienced
Schedule
Full-time
Job Level Code
M
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.