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Post Doctoral Fellow - Rockefeller Neuroscience Institute

West Virginia University Research Corporation is seeking applications for a Post Doctoral Fellow with the Rockefeller Neuroscience Institute (RNI).


Rockefeller Neuroscience Institute is the premier multidisciplinary institute for patient care, research, and teaching in West Virginia and the region. We celebrated the opening of our new Innovation Center on May 15, 2019. The RNI’s flagship facilities are located on the Health Sciences campus in Morgantown, with more than 1,000 dedicated team members across five departments, patient care units, and research laboratories. Find out more about our outstanding works and contributions today at: https://wvumedicine.org/rni/rni-homepage/newsroom/


About the Opportunity


The laboratory of Martin Hruska, Ph.D., in the Department of Neuroscience at West Virginia University and the Rockefeller Neuroscience Institute is seeking a highly motivated and creative post-doctoral researcher for the NIH-funded position related to structural and molecular mechanisms of synaptic remodeling during neurodegeneration and following an injury such as stroke. While the successful candidate's interest will be fitted with the laboratory interests, we are particularly looking to fill the position to investigate the synaptic mechanisms of functional recovery after stroke.


The efforts of the Hruska lab focus on investigating how the molecular nanoarchitecture of dendritic spine synapses underlies structural plasticity in health and disease. To do this, we have taken advantage of state-of-the-art stimulated-emission depletion (STED) super-resolution microscopy to examine how pre- and post-synaptic molecular nano-organization are linked across the synaptic cleft and how this organization changes with the structural plasticity of dendritic spines. We use STED in both fixed preparations (brain sections, cultured cells) and living cells to define how synaptic nanoarchitecture is dynamically modified after induction of structural plasticity. We are currently developing new reagents and techniques that will enable us to image thin brain sections to determine how neurological diseases impact the nanoarchitecture of synapses.


At WVU Research Corporation, we strongly believe in work-life balance and keeping time for things we love outside our work. WVU Research Corporation offers a comprehensive benefits package with a variety of options to suit your needs:


13 paid holidays (staff holiday calendar)PTO403(b) retirement savings with a fully vested 3% employee contribution match, (Employees have the option of contributing an additional 1-3% of their earnings to the plan, which is also matched by the WVURC)A range of health insurance and various other benefitsDependent Education ScholarshipWVU PerksAnd More!!

What you’ll do:


We seek highly self-motivated and creative post-doctoral researchers, particularly those who recently acquired Ph.D. or M.D. degree. Candidates with prior expertise in animal models of disease (hypoxia-ischemia, AD models) are encouraged to apply. Expertise in confocal and super-resolution imaging is advantageous. The lab has the new Leica Stellaris 8 STED system, and thus, we are set up for high/super-resolution imaging of synaptic structures both in vivo and in vitro.



Qualifications M.D. or PhD Previous experience with behavioral assessment and analysis. Surgical experience with animals preferably neurosurgery, dMCAO. Imaging experience preferably using confocal and two photon microscopy systems. Coding/generating macros in MATLAB and Image J. Working knowledge and experience in behavioral assessment and analysis. Working knowledge and experience in image acquisition and analysis. Experience in surgical procedures in animals Preparation of results for publication Versed in MATLAB, Image J or equivalent Requirements


Due to the nature of this job, it may or may not require Medical Monitoring



About Research Corporation


Why WVU Research Corporation?


The WVU Research Corporation (WVURC) was created as a not-for-profit corporation in 1985 to support research (R1) at West Virginia University. We provide evaluation, development, patenting, management, and marketing services for inventions of the faculty, staff and students of the University.


WVURC receives and administers funds awarded by external agencies for research and other activities and is responsible for helping protect intellectual property through patents, copyrights and licensing agreements for startup companies based on University research.


West Virginia University Research Corporation is proud to be an Equal Opportunity employer. We value diversity among its employees and invites applications from all qualified applicants regardless of race, ethnicity, color, religion, gender identity, sexual orientation, age, nationality, genetics, disability, or Veteran status.


Job Posting: Nov 30, 2021 Posting Classification: Research Corporation Exemption Status: Exempt Benefits Eligible: Yes Schedule: Full-time
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