Publications
Selected recent publications:
S. Panzavolta, M. Gioffrè, M. L. Focarete, C. Gualandi, L. Foroni, A. Bigi. Electrospun gelatin nanofibers: optimization of genipin crosslinking to preserve fiber morphology after exposure to water. Acta Biomater 2011; 7 1702–1709.
S. Panzavolta, P. Torricelli, B. Bracci, M. Fini, A. Bigi. Functionalization of biomimetic calcium phosphate bone cements with alendronate. J Inorg Biochem 2010; 104: 1099–1106.
E. Boanini, M. Gazzano, K. Rubini, A. Bigi. Collapsed Octacalcium Phosphate Stabilized by Ionic Substitutions. Crys Growth Des 2010; 10: 3612–3617.
E. Boanini, M. Gazzano, A. Bigi. Ionic substitutions in calcium phosphates synthesized at low temperature. Acta Biomater 2010; 6: 1882–1894.
E. Boanini, S. Panzavolta, K. Rubini, M. Gandolfi, A. Bigi. Effect of strontium and gelatin on the reactivity of a-tricalcium phosphate. Acta Biomater 2010; 6: 936–942.
E. Boanini, K. Rubini, S. Panzavolta, A. Bigi. Chemico-physical characterization of gelatin films modified with oxidized alginate. Acta Biomater 2010; 6: 383-388.
IN. Mihailescu, C Ristoscu, A Bigi, I Mayer. Advanced biomimetic implants based on nanostructured coatings synthesized by pulsed laser technologies. In Laser-Surface Interactions for New Materials Production: Tailoring Structure and Properties (Antonio Miotello, Paolo M. Ossi Eds. Springer, 2009, pp.235-260.
B. Bracci, P. Torricelli, S. Panzavolta, E. Boanini, R. Giardino, A. Bigi. Effect of Mg2+, Sr2+, and Mn2+ on the chemico-physical and in vitro biological properties of calcium phosphate biomimetic coatings. J Inorg Biochem 2009; 103: 1666–1674.
A. Bigi, E. Boanini, C. Capuccini, M. Fini, I.N. Mihailescu, C. Ristoscu, F. Sima, P. Torricelli. Biofunctional alendronate–Hydroxyapatite thin films deposited by Matrix Assisted Pulsed Laser Evaporation Biomaterials 2009; 30: 6168–6177.
C. Capuccini, P. Torricelli, E. Boanini, M. Gazzano, R. Giardino, A. Bigi. Interaction of Sr-doped hydroxyapatite nanocrystals with osteoclast and osteoblast-like cells. J Biomed Mater Res 2009, 89A:594-600.
S. Panzavolta, P. Torricelli, B. Bracci, M. Fini, A. Bigi. Alendronate and pamidronate calcium phosphate bone cements: Setting properties and in vitro response of osteoblast and osteoclast cells. J Inorg Biochem 2009; 103: 101-106.
S. Panzavolta, M. Fini, A. Nicoletti, B. Bracci, K. Rubini, R. Giardino, A. Bigi. Porous composite scaffolds based on gelatin and partially hydrolyzed a-tricalcium phosphate. Acta Biomater 2009; 5: 636–643.
C. Capuccini, P. Torricelli, F. Sima, E. Boanini, C. Ristoscu, B. Bracci, G. Socol, M. Fini, I.N. Mihailescu, A. Bigi. Strontium-substituted hydroxyapatite coatings synthesized by pulsed-laser deposition: in vitro osteoblast and osteoclast response. Acta Bio 2008; 4: 1885–1893
I.N. Mihailescu, S. Lamolle, G. Socol, F. Miroiu, F. J. Roenold, A. Bigi, I. Mayer, F. Cuisinier, S. P. Lingstadaas, In vivo tensile test of biomimetic titanium implants pulsed laser coated with nanostructured calcium phosphate thinfilms, Optoelectron. Adv. Mater. - Rapid Comm. 2008; 2: 337 – 341.
A. Bigi, M. Fini, B. Bracci, E. Boanini , P. Torricelli, G. Giavaresi, N. Nicoli Aldini, A. Facchini, F. Sbaiz, R. Giardino. The response of bone to nanocrystalline hydroxyapatite-coated Ti13Nb11Zr alloy in an animal model. Biomaterials 2008; 29: 1730-1736.
S. Panzavolta, P. Torricelli, L. Sturba, B. Bracci, R. Giardino, A. Bigi. Setting properties and in vitro bioactivity of strontium-enriched gelatin–calcium phosphate bone cements. J Biomed Mat Res 2008; 84: 965-972.
E. Boanini, P. Torricelli, M. Gazzano, R. Giardino, A. Bigi. Alendronate–hydroxyapatite nanocomposites and their interaction with osteoclasts and osteoblast-like cells. Biomaterials 2008; 29: 790-796.
S. Giannini, R. Buda, F. Di Caprio, P. Agati, A,.Bigi, V. De Pasquale, A. Ruggeri. Effects of freezing on the biomechanical and structural properties of human posterior tibial tendons. International Orthopaedics 2008; 32(2):145-51.
E. Boanini, M. Gazzano, K. Rubini, A. Bigi. Composite Nanocrystals Provide New Insight on Alendronate Interaction with Hydroxyapatite Structure. Adv. Mater. 2007, 19, 2499–2502.
S. Pezzatini, L. Morbidelli, R. Solito, E. Paccagnini, E Boanini, A. Bigi, M. Ziche. Nanostructured HA crystals up-regulate FGF-2 expression and activity in microvascular endothelium promoting angiogenesis. Bone 2007; 41: 523–534.
A. Bigi, N. Nicoli-Aldini, B. Bracci, B. Zavan, E. Boanini, F. Sbaiz, S. Panzavolta, G. Zorzato, R. Giardino, A. Facchini, G. Abatangelo, R. Cortivo. In vitro culture of mesenchymal cells onto nanocrystalline hydroxyapatite-coated Ti13Nb13Zr alloy. J Biomed Mater Res 2007; 82A: 213-221.
A. Bigi, E. Boanini, C. Capuccini, M. Gazzano. Strontium-substituted hydroxyapatite nanocrystals. Inorg Chim Acta 360 2007; 360:1009–1016.
E. Boanini, M. Fini, M. Gazzano, A. Bigi. Hydroxyapatite Nanocrystals Modified with Acidic Amino Acids. Eu. J. Inorg. Chem. 2006, 4821–4826
A. Bigi, S. Panzavolta, L. Sturba, P. Torricelli, M. Fini, R. Giardino. Normal and osteopenic bone-derived osteoblast response to a biomimetic gelatin-calcium phosphate bone cement. J Biomed Mater Res 2006; 78A: 739-745.
E. Boanini, P.Torricelli, M. Gazzano, R. Giardino, A. Bigi, Nanocomposites of hydroxyapatite with aspartic acid and glutamic acid and their interaction with osteoblast-like cells. Biomaterials 2006; 27: 4428–4433.
S. Pezzatini, R. Solito, L. Morbidelli, S. Lamponi, E. Boanini, A. Bigi, M. Ziche. The effect of hydroxyapatite nanocrystals on microvascular endothelial cell viability and functions. J. Biomed. Mater. Res. A 2006; 76:656-663.
E. Boanini, A. Bigi. Biomimetic synthesis of carbonated hydroxyapatite thin films. Thin Solid Films 2006; 497: 53-57.
