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Dr. Rahul Pratap Singh

Department of Pharmacy
GD Goenka University, India

Interests

1. Nanomedicines 2. Biomaterials and polymer science 3. Cancer diagnosis and treatment 4. Physicochemical characterization and interpretation 5. Pharmacokinetics and Pharmacological evaluation 6. Cancer cell targeting 7. Cancer therapy and diagnosis 8. Protein and peptide delivery 9. Receptor-targeting technique 10. Aptamer-functionalized drug delivery stems 11. In-vitro cancer cell line studies 12. In-vivo cancer induction and inhibition studies 13. Pharmacokinetic and tissue distribution studies

Projects

S. No. Title of Project Sponsoring Organization Period Date of Award Date of Completion Amount of Grant (in Rs.) Role 1 Studies on therapeutic aspects of nucleic acid aptamer-grafted-RGD receptor targeted theranostic chitosan-PLGA nanoparticles for brain cancer diagnosis and treatment Science and Engineering Research Board (SERB), New Delhi 39 Months 13/7/20 12/10/23 39,10969/- Principal Investigator 2 Development and pharmacological evaluation of multifunctional receptor-targeted nano enabled-drug delivery systems for lung cancer therapy GD Goenka University, Gurugram 24 Months 24/12/21 23/12/23 1,70000/- Principal Investigator Total Amount of Sanctioned Research Projects (in Rs.) 40,80969/-

Publications

S. No. Author(s) Title Name of Journal Impact Factor Volume Page Year Type of Authorship Type of Paper 1 Singh L, Bhakuni A, Monika, Singh RP, Arora S, Jhawat V Nanotechnology based topical insulin delivery system: promising role in diabetic wound healing Wound Repair and Regeneration 3.4 33 e70087 2025 Co-author Review 2 Rawat A, Chauhan S, Singh RP, Monika, Gupta S, Jhawat S Development and in-vitro optimization of telmisartan-curcumin solid dispersion nanoparticles for the management of diabetic nephropathy using DoE approach Drug Development and Industrial Pharmacy 2.2 In-print In-print 2025 Co-author Research 3 Verma J, Monika, Jhawat V, Shekhar S, Chauhan M, Sonali, Singh RP Eudragit RS100 nanoparticles for sustained release of cefpodoxime proxetil: preparation, pharmaceutical characterization, and in-vitro drug release studies Nanomedicine Journal 1.7 In-print In-print 2025 Corresponding Author Research 4 Deepshikha, Mathur P, Monika, Jhawat V, Shekhar S, Dutt R, Garg V, Arora S, Sonali, Singh RP An overview of hypertension: pathophysiology, risk factors, and modern management Current Hypertension Reviews 1.5 21(2) 64 - 81 2025 Corresponding Author Review 5 Verma J, Shekhar S, Monika, Chauhan M, Yadav B, Sonali, Singh RP Exploring pneumonia: understanding its epidemiology, deciphering pathogenic complexities, and developing advanced diagnostic and therapeutic approaches Current Respiratory Medicine Reviews 0.3 In-print In-print 2025 Corresponding Author Review 6 Dhandhi S, Yeshna, Vishal, Monika, Chauhan S, Singh M, Singh RP, Jhawat V Development and characterization of a gallic acid-infused topical emulgel for enhanced wound management: formulation and in vitro optimization RSC Pharmaceutics - 2 333 2025 Co-author Research 7 Singh RP, Sonali Current trends and challenges in targeting tumor mitochondrial glycolysis and oxidative phosphorylation pathways for cancer therapy Current Protein & Peptide Science 2.0 26(1) 2-5 2025 First and Corresponding Author Perspective 8 Monika, Singh RP Emerging trends and persistent challenges in nanomedicine for rheumatoid arthritis therapy Current Rheumatology Reviews 1.3 21(3) 207-211 2025 Corresponding Author Perspective 9 Chauhan S, Jhawat V, Singh RP, Yadav A Topical delivery of insulin using novel organogel formulations: An approach for the management of diabetic wounds Burns 2.9 50(5) 1068-1082 2024 Co-author Review 10 Rawat A, Chauhan S, Monika, Singh RP, Gupta S, Jhawat V. Preclinical pharmacology and pharmacokinetics of curcumin tagged cilostazol nanodispersion for the management of diabetic nephropathy in wister rat model In Silico Pharmacology 1.2 12(2) 81 2024 Co-author Research 11 Tanushree, Sharma A, Monika, Singh RP, Jhawat V. Human immunodeficiency virus infection challenges: Current therapeutic limitations and strategies for improved management through long-acting injectable formulation Reviews in Medical Virology 6.6 34(4) e2563 2024 Co-author Review 12 Yadav B, Chauhan M, Sonali, Dinkar R, Shekhar S, Gulia M, Singh RP In-silico modeling, development, characterization, in-vitro cytotoxicity, pharmacokinetic, and histopathological evaluation of folate-receptor targeted micelles containing cisplatin and upconversion nanoparticles for lung cancer therapy Materials Today Communications 4.5 39 109007 2024 Corresponding Author Research 13 Chauhan M, Sonali, Shekhar S, Yadav B, Garg V, Dutt R, Mehata AK, Goswami P, Koch B, Muthu MS, Singh RP AS1411 aptamer/RGD dual functionalized theranostic chitosan-PLGA nanoparticles for brain cancer treatment and imaging Biomaterials Advances 6.0 160 213833 2024 First and Corresponding Author Research 14 Yadav A, Jhawat V, Singh RP, Chauhan S, Dutt R, Goyal R, Singh D. Technical considerations, applications, and benefits of organogels in topical drug delivery systems Recent Advances in Drug Delivery and Formulation - 18(1) 12-20 2024 Co-author Review article 15 Garg P, Aggarwal N, Garg V, Dutt R, Singh RP, Kumar V, Chopra H, Al-Mazroua HA, Attia SM, Ahmad SF, Emran TB Assessment of antidepressant activity of stem of Jasminum multiflorum Andrews and Jasminum Mesnyi Hance by modulating neurochemicals and reducing oxidative stress Journal of Biological Regulators and Homeostatic Agents 0.8 38(2) 1649-1661 2024 Co-author Research 16 Chauhan S, Jhawat V, Singh RP, Yadav A, Garg V. Design, development and in-vitro characterization of insulin loaded topical pluronic-lecithin based organogel formulation for the management of diabetic wound Recent Advances in Drug Delivery and Formulation - 18(1) 50-60 2024 Co-author Research 17 Yadav B, Chauhan M, Singh RP, Sonali, Shekhar S. Recent progress and challenges in clinical translation of nanomedicines in diagnosis and treatment of lung cancer Current Drug Targets 2.5 25(1) 12-24 2024 Corresponding author Review 18 Chauhan S, Gulia M, Singh RP., Jhawat V Diabetic wound: pathophysiology, complications and treatment strategies Current Protein & Peptide Science 2.0 25(3) 200-205 2024 Co-author Editorial 19 Jogpal V, Sharma A, Singh RP, Jhawat V Computer simulation in pharmaceutical research and drug development for pharmacokinetic and therapeutic optimization Medical Journal Armed Forces India - 80(1) S35 4-S355 2024 Co-author Editorial 20 Yadav B, Chauhan M, Sonali, Dinkar R, Shekhar S, Singh RP Fabrication, in-silico, in-vitro, and in-vivo characterization of transferrin-targeted micelles containing cisplatin and gadolinium for improved theranostic applications in lung cancer therapy European Journal of Pharmaceutics and Biopharmaceutics 4.3 194 44-57 2023 Corresponding author Research 21 Chauhan M, Singh RP, Sonali, Yadav B, Shekhar S, Kumar L, Mehata AK, Jhawat V, Dutt R, Garg V, Kailashiya V, Muthu MS Dual-targeted transferrin and AS1411 aptamer conjugated micelles for improved therapeutic efficacy and imaging of brain cancer Colloids and Surfaces B: Biointerfaces 5.6 231 113544 2023 Corresponding author Research 22 Chauhan M, Singh RP, Sonali, Yadav B, Shekhar S, Kumar A, Mehata AK, Nayak AK, Dutt R, Garg G, Kailashiya V, Muthu MS, Koch B, Pandey DK Development and characterization of micelles for nucleolin-targeted co-delivery of docetaxel and upconversion nanoparticles for theranostic applications in brain cancer therapy Journal of Drug Delivery Science and Technology 4.9 87 104808 2023 Corresponding author Research 23 Dhir S, Dutt R, Singh RP, Chauhan M, Virmani T, Kumar G, Alhalmi A, Aleissa MS, Rudayni HA, Al-Zahrani M. Amomum subulatum fruit extract mediated green synthesis of silver and copper oxide nanoparticles: synthesis, characterization, antibacterial and anticancer activities Processes 2.8 11 2698 2023 Co-author Research 24 Chauhan M, Singh RP, Sonali, Zia G, Shekhar S, Yadav B, Garg V, Dutt R An overview of current progress and challenges in brain cancer therapy using advanced nanoparticles Recent Patents on Nanotechnology 3.1 18(3) 295 - 304 2023 Corresponding author Editorial 25 Yadav B, Chauhan M, Shekhar S, Nayak AK, Dutt R, Sonali, Singh RP Micelles-based drug delivery systems: implication, challenges and future perspectives in lung cancer therapy Current Protein & Peptide Science 2.0 24 (4) 285 - 287 2023 Corresponding author Editorial 26 Yadav B, Chauhan M, Shekhar S, Kumar A, Mehata AK, Nayak AK, Dutt R, Garg V, Kailashiya V, Muthu MS, Sonali, Singh RP RGD-decorated PLGA nanoparticles improved effectiveness and safety of cisplatin for lung cancer therapy International Journal of Pharmaceutics 5.2 633 122587 2023 Corresponding author Research 27 Jhawat V, Sharma A, Singh RP, In-silico computational tools in effective product design and pharmacokinetics optimization Clinical Case Reports International - 6 1324 2022 Co-author Editorial 28 Shekhar S, Chauhan M, Sonali, Yadav B, Dutt R, Hu L, Muthu MS, Singh RP Enhanced permeability and retention effect-focused tumor-targeted nanomedicines: latest trends, obstacles and future perspective Nanomedicine (Lond) 3.9 17 (18) 1213-1216 2022 Corresponding author Editorial 29 Sinha S, Sonali, Garg V, Thapa S, Singh S, Chauhan M, Dutt R, Singh RP Empagliflozin containing chitosan-alginate nanoparticles in orodispersible film: preparation, characterization, pharmacokinetic evaluation and its in-vitro anticancer activity Drug Development and Industrial Pharmacy 2.2 48 (7) 279-291 2022 Corresponding author Research 30 Chauhan M, Shekhar S, Yadav B, Garg V, Dutt R, Sonali, Singh RP Nanoparticles: a promising tool to promote reactive oxygen species in cancer therapy Current Protein & Peptide Science 2.0 22 (12) 827-830 2021 Corresponding author Editorial 31 Sinha S, Garg V, Sonali, Singh RP, Dutt R Chitosan-alginate core-shell-corona shaped nanoparticles of dimethyl fumarate in orodispersible films improved bioavailability for treatment of multiple sclerosis: preparation, characterization and biodistribution in rats Journal of Drug Delivery Science and Technology 4.9 64 102645 2021 Corresponding author Research 32 Liu H, Singh RP, Zhang Z, Han X, Liu Y, Hu L. Microfluidic assembly: an innovative tool for the encapsulation, protection, and controlled release of nutraceuticals Journal of Agricultural and Food Chemistry 6.2 69 (10) 2936-2949 2021 First co-author Review 33 Yu J, Zhang Z, Li X, Singh RP, Liu Y, Hu L. Preparation and characterization of advanced resin based drug delivery system to improve therapeutic efficacy of huperzine A Journal of Drug Delivery Science and Technology 4.9 61 102335 2021 Co-author Research 34 Liu H, Hua L, Singh RP, Dave B, Chen J, Yu J. Fabrication of a novel drug-resin combination device for controlled release of dextromethorphan hydrobromide. Colloids and Surfaces B: Biointerfaces 5.6 189 110833 2020 Second co-author Research 35 Singh RP, Sharma G, Sonali, Singh S, Bharti S, Pandey BL, Koch B, Muthu MS. Chitosan-folate decorated carbon nanotubes for site specific lung cancer delivery Materials Science and Engineering: C 7.9 77 446-458 2017 First author Research 36 Singh RP, Sharma G, Sonali, Singh S, Patne SCU, Pandey BL, Koch B, Muthu MS. Effects of transferrin conjugated multi-walled carbon nanotubes in lung cancer delivery Materials Science and Engineering: C 7.9 67 313-325 2016 First author Research 37 Singh RP, Sharma G, Sonali, Singh S, Kumar M, Pandey BL, Koch B, Muthu MS. Vitamin E TPGS conjugated carbon nanotubes improved efficacy of docetaxel with safety for lung cancer treatment. Colloids and Surfaces B: Biointerfaces 5.6 141 429-442 2016 First author Research 38 Singh RP, Sharma G, Sonali, Agrawal P, Pandey BL, Koch B, Muthu MS. Transferrin receptor targeted PLA-TPGS micelles improved efficacy and safety in docetaxel delivery. International Journal of Biological Macromolecules 8.5 83 335-344 2016 First author Research 39 Sonali, Viswanadh MK, Singh RP, Agrawal P, Mehata AK, Pawde DM, Narendra, Sonkar R, Muthu MS. Nanotheranostics: Emerging strategies for early diagnosis and therapy of brain cancer Nanotheranostics - 2 (1) 70-86 2018 Second co-author Review 40 Agrawal P, Singh RP, Sonali, Kumari L, Sharma G, Koch B, Rajesh CV, Mehata AK, Singh S, Pandey BL, Muthu MS. TPGS-chitosan cross-linked targeted nanoparticles for effective brain cancer therapy. Materials Science and Engineering: C 7.9 74 167-176 2017 First co-author Research 41 Agrawal P, Sonali, Singh RP, Sharma G, Mehata AK, Singh S, Rajesh CV, Pandey BL, Koch B, Muthu MS. Bioadhesive micelles of D-α-tocopherol polyethylene glycol succinate 1000: Synergism of chitosan and transferrin in targeted drug delivery. Colloids and Surfaces B: Biointerfaces 5.6 152 277-288 2017 Second co-author Research 42 Sonali, Singh RP, Sharma G, Kumari L, Koch B, Singh S, Bharti S, Rajinikanth PS, Pandey BL, Muthu MS. RGD-TPGS decorated theranostic liposomes for brain targeted delivery. Colloids and Surfaces B: Biointerfaces 5.6 147 129-141 2016 First co-author Research 43 Kaklotar D, Agrawal P, Abdulla A, Singh RP, Mehata AK, Singh S, Mishra B, Pandey BL, Trigunayat A, Muthu MS. Transition from passive to active targeting of oral insulin nanomedicines: enhancement in bioavailability and glycemic control in diabetes Nanomedicine (Lond) 3.9 11 (11) 1465-1486. 2016 Third co-author Review 44 Sonali, Singh RP, Singh N, Sharma G, Vijayakumar MR, Koch B, Singh S, Singh U, Dash D, Pandey BL, Muthu MS. Transferrin liposomes of docetaxel for brain-targeted cancer applications: formulation and brain theranostics. Drug Delivery 8.1 23 (4) 1261-1271 2016 First co-author Research 45 Sonali, Agrawal P, Singh RP, Rajesh CV, Singh S, Vijayakumar MR, Pandey BL, Muthu MS Transferrin receptor-targeted vitamin E TPGS micelles for brain cancer therapy: preparation, characterization and brain distribution in rats Drug Delivery 8.1 23 (5) 1788-1798 2016 Second co-author Research 46 Singh RP, Sonali, Mehata AK, Agrawal P, Singh S, Muthu MS. Carbon nanotubes: super-fabric tiny materials as lung cancer theranostics. The Pharmstudent - 27 55-78 2016 First author Review 47 Muthu MS, Agrawal P, Singh RP. Antipsychotic nanomedicine: a successful platform for clinical use. Nanomedicine (Lond) 3.9 9 (14) 2071-2074 2014 Second co-author Editorial 48 Sonali, Singh RP, Prajapati SK. Formulation and evaluation of prednisolone loaded microsponges for colon drug delivery: in-vitro and pharmacokinetic study. International Journal of Pharmaceutical Sciences and Research - 5 (5) 1994-2005 2014 First co-author Research 49 Joshi H, Singh BK, Saxena G, Singh V, Singh RP, Arya E. Novel halogens substituted coumarin-aldehyde as an anti-inflammatory agent. World Journal of Pharmacy and Pharmaceutical Sciences - 2 (3) 1-15 2013 Co-author Research 50 Joshi H, Saxena GK, Singh V, Arya E, Singh RP. Phytochemical investigation, isolation and characterization of betulin from bark of Betula Utilis. Journal of Pharmacognosy and Phytochemistry - 2 (1) 145-151 2013 Co-author Research 51 Singh RP, Singh S, Prajapati SK, Saxena GK. Nimesulide loaded microsponges: in-vitro and ex-vivo evaluation. International Journal of Biopharmaceutics - 4 (1) 49-60 2013 First and corresponding author Research 52 Joshi H, Singh BK, Saxena GK, Singh V, Singh RP., Arya E. Synthesis and characterization of novel halogens substituted coumarin-Aldehyde. International Journal of Chemical and Pharmaceutical Sciences - 4 (1) 19-23 2012 Co-author Research 53 Sonali, Singh RP, Viswanadh MK, Singh S, Muthu MS. Mesoporous silica nanoparticles for brain cancer theranostics. The Pharmstudent - 28 36-44 2017 First co-author Review 54 Sinha S., Dutt R, Singh RP. Quality by design in pharmaceutical product development Acta Scientific Pharmaceutical Sciences - 3 (1) 70-72 2018 Corresponding author Review
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Grade: Registered User

Member since September 7, 2024
Contact Details
Address: Department of Pharmacy, School of Healthcare and Allied Sciences, GD Goenka University, Sohna, Gurugram, Haryana, India
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