Publications
Plomp, P.J.A.M., Wolvetang, E.J., Groen, A.K., Meijer, A.J., Gordon, P.B. and Seglen, P.O. Energy dependence of autophagic protein degradation in isolated rat hepatocytes (1987) Eur.J.Biochem. 164, 197-203.
2. Caro, L.H.P., Plomp, P.J.A.M., Wolvetang, E.J., Kerkhof, C. and Meijer A.J. 3-methyl adenine, an inhibitor of autophagy, has multiple effects on metabolism (1988) Eur.J.Biochem. 175, 325-329.
3. Wolvetang, E.J., Wanders, R.J.A., Berden, J., Schutgens, R.B.H. and Tager, J.M. Properties of the ATPase activity associated with peroxisome enriched fractions from rat liver: comparison with mitochondrial F1FO-ATPase (1990) Biochim.Biophys.Acta 1035, 6-11.
4. Wolvetang, E.J., Tager, J.M. and Wanders, R.J.A. Latency of the peroxisomal enzyme dihydroxyacetonephosphate acyltransferase (DHAP-AT) in permeabilized human skin fibroblasts (1991) Biochem.Biophys.Res.Commun. 170, 1135-1143.
5. Wolvetang, E.J., Tager, J.M. and Wanders, R.J.A. Factors influencing the latency of the peroxisomal enzyme dihydroxyacetonephosphate acyltransferase (DHAP-AT) in permeabilized human skin fibroblasts (1991) Biochim.Biophys.Acta 1095, 122-126.
6. Wolvetang, E.J., Tager, J.M. and Wanders, R.J.A. Structure linked latency of peroxisomal fatty acid metabolism in human skin fibroblasts: novel insights on peroxisomal permeability (1992) in Clinical, Biochemical and Molecular Aspects of Fatty Acid Oxidation (Coates, P. and Tanaka, Y. Eds.) John Wiley & Sons Inc., New York, U.S.A., pp. 101-108.
7. Wolvetang, E.J., Tager, J.M. and Wanders, R.J.A. Restricted permeability of peroxisomes in digitonin permeabilized cells (1992) in Adenine Nucleotides in Cellular Energy Transfer and Signal Transduction (Papa, S., Azzi, A. and Tager, J.M. Eds.) Birkhauser Verlag, Basel, Switzerland, pp. 423-435.
8. Wolvetang, E.J., Tager, J.M. and Wanders R.J.A. Latency of peroxisomal palmitoyl-CoA beta-oxidation in digitonin permeabilized fibroblasts: the effect of ATP on peroxisomal permeability. (1992) Prog. Clin. Biol.Res. 375, 223-229.
9. Wolvetang, E.J., Johnson, K.L., Krauer, K., Ralph, S.J. and Linnane, A.W. Mitochondrial respiratory chain inhibitors induce apoptosis (1994) FEBS Lett. 339, 40-44.
10. Wolvetang, E.J., Degli Esposti, Linnane, A.W. and Lawen, A. Induction of apoptosis by mitochondrial complex I inhibitors capsaicin and rotenone differs in Bcl-2 sensitivity and calcineurin involvement. (1994) Biol.Chem. Hoppe-Seyler 375, supl. 1, S 113.
11. Lawen, A., Martinus, R.D., Mc Mullen, G., Nagley, P., Vaillant, F., Wolvetang, E.J., Linnane, A.W. The universality of bioenergetic disease: the role of mitochondrial DNA mutations and the putative inter-relationship between mitochondria and the plasma membrane NADH oxido reductase. (1994) Molec.Asp.Med. 15, 13-27.
12. Larm, J.A., Wolvetang, E.W. Vaillant, F., Lawen, A. and Linnane, A.W. Plasma membrane oxidoreductase activity is not correlated with the production of extracellular superoxide radicals. (1995) Protoplasma, 184, 173-180.
13 Grubb. D.R., Wolvetang, E.J. and Lawen, A. Didemnin B induces cell death by apoptosis: the fastest apoptosis ever described (1995) Biochem.Biophys.Res.Commun. 215, (3) 1130-1136.
14 Vaillant, F., Larm, J.A, McMullen, G.L., Wolvetang, E.J. and Lawen, A. Effectors of the mammalian plasma membrane NADH-oxidoreductase system. Short-chain ubiquinone analogues as potent stimulators. (1996)
J. Bioenerg. Biomemb. 28, 531-540.
15 Wolvetang, E.J., Larm, J., Matsoulas, P. and Lawen, A. Induction of apoptosis by inhibitors of plasma membrane NADH-oxidase; a pathway involving Bcl-2 and calcineurin. (1996) Cell Growth and Diff. 7, 1315-1325.
16 De Haan, J.B., Wolvetang, E.J., Cristiano, F., Ianello, R., Bladier, C., Kelner, M.J. and Kola, I. Reactive oxygen species and their contribution to pathology in Down syndrome” (1996) Adv. Pharmacol. 38, 379-402.
17 Bladier, C., Wolvetang, E.J., Hutchinson P., de Haan J.B., and Kola I. Response of a primary human fibroblast cell line to H2O2; senescence-like growth arrest or apoptosis? (1997) Cell Growth and Diff. 8, 589-598.
18 Lacey DC, Yang YH, Hutchinson P, Wolvetang E, Leech M, Morand EF. Regulation of apoptosis/proliferation and p53 by MIF in RA fibroblast-like synoviocytes. (2001) Arthritis and Rheumatism 44, 9, S158-S158 .
19 Hertzog PJ, Pritchard M, Wolvetang E, Wilson T, Owczarek CM, Kola I. Function of two gene families on human chromosome 21 and their potential contribution to Down syndrome. (2001) Cytogenetics and cell genetics ,1-2, 92, 12-21.
20 Lazner, F., Wolvetang, E.J., Lazner, D. and Hertzog, P. Bone disease: Current knowledge and future prospects. (2001) Curr. Genomics 2, 91-124.
21 Sanij E , Hatzistavrou T, Hertzog P. Crack P, Kola I, Wolvetang E.J. Induction of the transcription factor Ets-2 in response to oxidative and genotoxic stress. Biochem.Biophys. Res.Comm. (2001) 287,(4) 1003-1008.
22 Sanij E, Scott B, Wilson T, Xu D, Hertzog P, Wolvetang E. Characterization of monoclonal antibodies specific to the transcriptionfactor Ets2 protein. Immunol. Lett. (2003), 86 (1), 63 – 70.
23 Wolvetang, E.J., Wilson, T., Busciglio, J., Sanij, E., Lazner, D., Hatzistavrou, T., Seth, A., Hertzog, P. and Kola I. ETS2 overexpression in transgenic models and in Down sydrome predisposes to apoptosis via the p53 pathway (2003) Hum Mol Genet 12 (3), 247-255.
24 Wolvetang, E.J., Bradfield, O., ., Hatzistavrou, T, Crack, PJ, Busciglio J., Zavarsek, S., Kola, I. and Hertzog, P. ETS2 induces neuronal apoptosis. (2003) Neurobiol. of Disease 14, (3) 349-356.
25 Wolvetang, E.J , Bradfield OM, Tymms, M., Zavarsek S, Hatzistavrou T, Kola I and Hertzog P (2003) The chromosome 21 transcription factor ETS2 transactivates the -APPpromoter :implications for Down syndrome. BBA Gene Expression (2003) 28, 1628 (2), 105-110.
26 Leech M, Lacey D, Xue JR, Santos L, Hutchinson P, Wolvetang E, David JR, Bucala R, Morand EF. (2003) Regulation of p53 by macrophage migration inhibitory factor in inflammatory arthritis. Arthritis Rheum. 48(7), 1881-1889.
27 Ohtani N., Brennan, P., Gaubatz S., Sanij E., Hertzog P., Wolvetang E.J., Ghysdeal J., Rowe M., Hara E. (2003) Epstein-Barr virus LMP1 blocks p16INK4A/Rb-pathway by promoting nuclear export of Ets2 and E2F4/5. J. Cell Biol. 162 (2), 173-183.
28 Thouas GA, Trounson AO, Wolvetang EJ and Jones GM (2004) Mitochondrial dysfunction in oocytes results in embryo developmental arrest in vitro. Biol.Rep. 71 (6), 1936-42.
29 Helguera P, Pelsman A, Pigino G, Wolvetang E, Head E, Busciglio J. (2005) Ets-2 Promotes the Activation of a Mitochondrial Death Pathway in Down's Syndrome Neurons. J Neurosci. 25 (9), 2295-2303.
30 Pebay A., Wong R., Pitson SM., Wolvetang E., Peh GS., Filipczyk A., Koh KL., Tellios I., Nguyen LT., Pera MF. (2005) Essential roles of sphingosine-1-phosphate and platelet-derived growth factor in the maintenance of human embryonic stem cells.
Stem Cells. 23 (10):1541-1548.
31 Wolvetang E ,Herszfeld D, Langton –Bunker E, Chung T, Filipczyk A, Houssami S, Koh K, Laslett AL, Michalska A, Nguyen L, Reubinoff BE, Tellis I, Auerbach JM, Ording CJ, Looijenga LHJ, and Pera MF. (2006) CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells. Nat.Biotech. 24(3):351-7.
32 Grandela C and Wolvetang E. (2007) hESC Adaptation, Selection and Stability. Stem Cell Rev. 2007 Fall;3(3):183-91.
33 Grandela, C., Pera, M.F., Grimmond, S.M., Kolle, G., Wolvetang, E.J. p53 is required for etoposide-induced apoptosis of human embryonic stem cells. (2007) Stem Cell Research 1 (2) Pages 116-128.
34 Wolvetang EJ, Pera MF, Zuckerman KS. Gap-junction mediated transport of shRNA between human embryonic stem cells. (2007) Biochem.Biophys. Res.Comm. 363(3):610-5.
35 Davidson, KC; Daly, R; Wolvetang, EJ, et al . Wnt signaling in human embryonic stem cells.. (2007) Book chapter: Cytometry part A Volume: 69A Issue: 5 Pages: 412-412.
36 Méabh Cullinane, Lan Gong, Natalie Lazar-Adler, Thien Tra, Ernst Wolvetang, Mark Prescott, John D. Boyce, Rodney J. Devenish., and Ben Adler. Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines. (2008) Autophagy. 4 (6):744-53.
37 Hannan, NRF and EJ Wolvetang. Adipocyte differentiation in human embryonic stem cells transduced with Oct4 shRNA lentivirus. (2008) Stem Cell Dev. 18(4):653-60.
38 Prowse ABJ, Wolvetang EJ, Gray PP. A rapid, cost effective method for counting human embryonic stem cell numbers as clumps. (2009) Biotechniques. 47(1):599-606.
39 N Hannan, P Jamshidi, MF Pera, EJ Wolvetang. BMP -11 and Myostatin Maintain Human Embryonic Stem Cells in Feeder Free Cultures. (2009) Cloning and Stem Cells 11(3):427-35.
40 Andrew B J Prowse, John Wilson, Geoffrey W Osborne, Peter P Gray and Ernst J Wolvetang. Multiplexed staining of live human embryonic stem cells for flow cytometric analysis of pluripotency markers” (2009) Stem Cells and Development. 18(8):1135-40.
41 Michael R. Doran, Jessica E. Frith, Andrew B. J. Prowse, Jane Fitzpatrick, Ernst Wolvetang, Trent Munro, Peter Gray, Justin Cooper-White. Defined high protein content surfaces for stem cell culture (2010) Biomaterials 31(19):5137-42.
42 Tung-Liang Chung, Romulo M. Brena, Gabriel Kolle, Sean M Grimmond, Benjamin P. Berman, Peter W. Laird, Martin F. Pera and Ernst J. Wolvetang. Vitamin C promotes widespread yet specific demethylation of the hESC epigenome. (2010) Stem Cells 28(10):1848-55.
43 Tung-Liang Chung, Jennifer Turner, Nilay Thakar, Gabriel Kolle, Justin Cooper-White, Sean M Grimmond, Martin F. Pera, Ernst Wolvetang. Ascorbate Promotes Epigenetic activation of CD30 in Human Embryonic Stem Cells. (2010) Stem Cells 28(10):1782-93
44 Prowse A, Doran M, Cooper-White J, Chong F, Munro T, Fitzpatrick J, Chung TL, Haylock DN, Gray PP, Wolvetang E. Long term culture of human embryonic stem cells on recombinant vitronectin in ascorbate free media. (2010) Biomaterials Nov;31(32):8281-8.
45 Hudson JE, Mills RJ, Frith JE, Brooke G, Jaramillo-Ferrada P, Wolvetang EJ, Cooper-White JJ. A Defined Media and Substrate for Expansion of Human Mesenchymal Stromal Cell Progenitors that Enriches for Osteo- and Chondro-genic Precursors. Stem Cells Dev. (2010) 20(1):77-87.
46 Tung-Liang Chung, Nilay Thaker, Wolvetang EJ. Genetic and epigenetic instability of human pluripotent stem cells. The Open Stem Cell Journal (2010). (In press)
47 Hudson JE, Frith JE, Donose BC, Rondeau E, Mills RJ, Wolvetang EJ, Brooke GP, Cooper-White JJ. A synthetic elastomer based on acrylated polypropylene glycol triol with tunable modulus for tissue engineering applications. Biomaterials. (2010) Nov;31(31):7937-47.
48 Ovchinnikov DA and E J Wolvetang. Smads – the intracellular hubs of signalling in regulation of pluripotency and differentiation of stem cells. (2011) In: Embryonic Stem Cells: The Hormonal Regulation of Pluripotency and Embryogenesis. ISBN 978-953-307-196-1 Edited by: Craig Atwood, Publisher: InTech.
49 Alejandra M. Vitale, Ernst Wolvetang, Alan Mackay-Sim. Induced pluripotent cells: a new technology to study human diseases. (2011) The International Journal of Biochemistry and Cell Biology. (accepted for publication).
50 James E Hudson, Gary Brooke, Chris Blair, Ernst Wolvetang, Justin Cooper-White. Development of Myocardial Constructs Using Modulus-Matched Acrylated Polypropylene Glycol Triol (aPPGT) Substrates and Different Non-Myocyte Cell Populations. (2011) Tissue Engineering Part A (accepted for publication).
