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Frank Gu

Chemical Engineering
University of Waterloo

Publications

Gu F, Langer R, Farokhzad OC, "Formulation/preparation of functionalized nanoparticles for in vivo targeted drug delivery," Methods in Molecular Biology, 544, 589-598, 2009.
Dhar S, Gu FX, Langer R, Farokhzad OC, Lippard SJ, "Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles," Proceedings of the National Academy of Sciences of the United State of America, 105(45), 17356-61, Nov. 2008.
Karnik R, Gu F, Basto P, Cannizzaro C, Dean L, Kyei-Manu W, Langer R, Farokhzad OC, "Microfluidic platform for controlled synthesis of polymeric nanoparticles," Nano Letters, 8(9), 2906-12, Sep. 2008.
Wang AZ, Bagalkot V, Vasilliou CC, Gu F, Alexis F, Zhang L, Shaikh M, Yuet K, Cima MJ, Langer R, Kantoff PW, Bander NH, Jon S, Farokhzad OC, "Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy," ChemMedChem, 3(9), 1311-5, Sep. 2008.
Zhang L, Chan JM, Gu FX, Rhee JW, Wang AZ, Radovic-Moreno AF, Alexis F, Langer R, Farokhzad OC, "Self-assembled lipid-polymer hybrid nanoparticles: a robust drug delivery platform," ACS Nano, 2(8), 1696-702, Aug. 2008.
Zhang L, Gu FX, Chan JM, Wang AZ, Langer RS, Farokhzad OC, "Nanoparticles in medicine: therapeutic applications and developments," Clinical Pharmacology and Therapeutics, 83(5), 761-9, May 2008.
Gu F, Zhang L, Teply BA, Mann N, Wang A, Radovic-Moreno AF, Langer R, Farokhzad OC, "Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers," Proceedings of the National Academy of Sciences, 105(7), 2586-91, Feb. 2008.
Townsend SA, Evrony GD, Gu FX, Schulz MP, Brown RH Jr, Langer R, "Tetanus toxin C fragment-conjugated nanoparticles for targeted drug delivery to neurons," Biomaterials, 28(34), 5176-84, Dec. 2007.
Zhang L, Radovic-Moreno AF, Alexis F, Gu FX, Basto PA, Bagalkot V, Jon S, Langer RS, Farokhzad OC, "Co-delivery of hydrophobic and hydrophilic drugs from nanoparticle-aptamer bioconjugates," ChemMedChem, 2(9), 1268-71, Sep. 2007.
Casari BM, Langer V, "A pseudo-merohedrally twinned rare-earth sulfate: K6[Ce(HSO4)2(SO4)4].H2O, a novel structure type," Acta Crystallographica Section C: Crystal Structure Communications, 63(Pt 4), i25-7, Apr. 2007.
Gu F, Neufeld R, Amsden B, "Maintenance of vascular endothelial growth factor and potentially other therapeutic proteins bioactivity during a photo-initiated free radical cross-linking reaction forming biodegradable elastomers," European Journal of Pharmaceutics and Biopharmaceutics, 66(1), 21-7, Apr. 2007.
Cheng J, Teply BA, Sherifi I, Sung J, Luther G, Gu FX, Levy-Nissenbaum E, Radovic-Moreno AF, Langer R, Farokhzad OC, "Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery," Biomaterials, 28(5), 869-76, Feb. 2007.
Gu F, Neufeld R, Amsden B, "Sustained release of bioactive therapeutic proteins from a biodegradable elastomeric device," Journal of Controlled Release, 117(1), 80-9, Jan. 2007.
Larsson KH, Parmasto E, Fischer M, Langer E, Nakasone KK, Redhead SA, "Hymenochaetales: a molecular phylogeny for the hymenochaetoid clade," Mycologia, 98(6), 926-36, Nov.-Dec. 2006.
Gu F, Neufeld R, Amsden B, "Osmotic-driven release kinetics of bioactive therapeutic proteins from a biodegradable elastomer are linear, constant, similar, and adjustable," Pharmaceutical Research, 23(4), 782-9, Apr. 2006.
Gu F, Younes HM, El-Kadi AO, Neufeld RJ, Amsden BG, "Sustained interferon-gamma delivery from a photocrosslinked biodegradable elastomer," Journal of Controlled Release, 102(3), 607-17, Feb. 2005.
Amsden BG, Misra G, Gu F, Younes HM, "Synthesis and characterization of a photo-cross-linked biodegradable elastomer," Biomacromolecules, 5(6), 2479-86, Nov.-Dec. 2004.
Gu F, Amsden B, Neufeld R, "Sustained delivery of vascular endothelial growth factor with alginate beads," Journal of Controlled Release, 96(3), 463-72, May 2004.
Member
Grade: Member

Member since May 16, 2011
Contact Details
Address: 200 University Ave West, Waterloo, ON, Canada
Phone: 519 888 4567 ext 38605
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