Publications
http://www.dti.supsi.ch/~pavan/
*: as corresponding author
2011 (7)
21. L. Albertazzi, M. Brondi, G.M. Pavan, S. Sulis Sato, G. Signore, B. Storti, G.M. Ratto and F. Beltram. Dendrimer-based fluorescent indicators: in vitro and in vivo applications. PLoS ONE, 2011, 6: e28450.
20. G.M. Pavan* and A. Danani. Supporting the design of efficient DNA and siRNA nano-carriers with molecular modeling. Curr. Drug Discov. Tech., 2011, 8(4), 314-328.
19. G.M. Pavan*, M.A. Kostiainen and A. Danani. Protein-dendron conjugates for DNA binding: understanding the effect of the protein core on multivalency. RSC Adv., 2011, 1, 1677-1681.
18. M. Shema-Mizrachi, G.M. Pavan, E. Levin, A. Danani and N.G. Lemchoff. Catalytic chameleon dendrimers. J. Am. Chem. Soc., 2011, 133, 14359–14367.
17. L.B. Jensen, G.M. Pavan, M.R. Kasimova, S. Rutherford, A. Danani, H.M. Nielsen and C. Foged. Elucidating the molecular mechanism of PAMAM-siRNA dendriplex self-assembly: effect of dendrimer charge density. Int. J. Pharm., 2011, 416, 410-418.
16. O.M. Merkel, M. Zeng, M.A. Mintzer, G.M. Pavan, D. Librizzi, M. Maly, H. Höffken, A. Danani, E.E. Simanek and T. Kissel. Molecular modeling and in vivo imaging can identify successful hyperflexible triazine dendrimer-based siRNA delivery system. J. Contr. Release, 2011, 153, 23–33.
15. G. Doni, M.A. Kostiainen, A. Danani and G.M. Pavan*. Generation-dependent molecular recognition controls self-assembly in supramolecular dendron-virus complexes. Nano Lett., 2011, 11, 723-728.
2010 (8)
14. L.B. Jensen, K. Mortensen, G.M. Pavan, M.R. Kasimova, D.K. Jensen, V. Gadzhyeva, H.M. Nielsen and C. Foged. Molecular characterization of the interaction between siRNA and PAMAM G7 dendrimers by SAXS, ITC and molecular Simulations. Biomacromolecules, 2010, 11, 3571-3577.
13. G.M. Pavan* and A. Danani. The influence of dendron’s architecture on the “rigid” and “flexible” behaviour in Binding DNA – a modelling study. Phys. Chem. Chem. Phys., 2010, 12, 13914-13917.
12. G.M. Pavan, P. Posocco, A. Tagliabue, M. Maly, A. Malek, A. Danani, E. M. Ragg, C. Catapano and S. Pricl. PAMAM dendrimers for siRNA delivery: computational and experimental insights. Chem. Eur. J., 2010, 16, 7781-7795.
11. M.A. Kostiainen, J. Kotimaa, M-L. Laukkanen and G.M. Pavan. Optically degradable dendrons for temporary adhesion of proteins to DNA. Chem. Eur. J., 2010, 16, 6912-6918.
10. G.M. Pavan*, M.A. Kostiainen and A. Danani. Computational approach for understanding the interactions of UV-degradable dendrons with DNA and siRNA. J. Phys. Chem. B., 2010, 114, 5686-5693.
9. S.P. Jones, G.M. Pavan*, A. Danani, S. Pricl and D.K. Smith. Quantifying the effect of surface ligands on dendron-DNA interactions – insights into multivalency through a combined experimental and theoretical approach. Chem. Eur. J., 2010, 16, 4519-4532.
8. G.M. Pavan*, L. Albertazzi and A. Danani. Ability to adapt: studying the behavior of different generations of PAMAM dendrimers in siRNA binding. J. Phys. Chem. B., 2010, 114, 2667-2675.
7. G.M. Pavan*, M.A. Mintzer, E.E. Simanek, O.M. Merkel, T. Kissel and A. Danani. Computational insights into the interactions between DNA and RNA with “rigid” and “flexible” triazine dendrimers. Biomacromolecules, 2010, 11, 721-730.
2009 (4)
6. G.M. Pavan*, A. Danani, S. Pricl and D.K. Smith. Modeling the multivalent recognition between dendritic molecules and DNA – understanding how ligand sacrifice and shielding may enhance binding. J. Am. Chem. Soc., 2009, 131, 9686-9694.
5. E. Conca, T. Negri, A. Gronchi, E. Fumagalli, E. Tamborini, G.M. Pavan, M. Fermeglia, M.A. Pierotti, S. Pricl and S. Pilotti. Activate and resist: L576P-KIT in GIST. Mol. Cancer Ther., 2009, 8, 2491-2495.
4. S.E. Woodman, J.C. Trent, K. Stemke-Hale, A.J. Lazar, S. Pricl, G.M. Pavan, M. Fermeglia, Y.N. Gopal, D. Yang, D.A. Podoloff, D. Ivan, K.B. Kim, N. Papadopoulos, P. Hwu, G.B. Mills and M.A. Davies. Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates. Mol. Cancer Ther., 2009, 8, 2079-2085.
3. T. Negri, G.M. Pavan, E. Virdis, A. Greco, M. Fermeglia, M. Sandri, S. Pricl, M.A. Pierotti, S. Pilotti and E. Tamborini. T670X KIT mutations in GISTs: making sense of missense. J. Natl. Cancer Inst., 2009, 101, 194-204.
2008 (2)
2. J.C. McAuliffe, W.L. Wang, G.M. Pavan, S. Pricl, D. Yang, S.S. Chen, A.J.F. Lazar, R.E. Pollock and J.C. Trent. Unlucky number 13? Differential effects of KIT exon 13 mutation in gastrointestinal stromal tumors. Molecular Oncology, 2008, 2, 161-163.
1. P. Posocco, G.M. Pavan, G. Scocchi, J.W. Handgraaf, A. Malek, M. Maly, M. Fermeglia, J.G.E.M. Fraaije, C.V. Catapano, A. Danani and S. Pricl. Base Invaders. Coupling Experiments and Multiscale Modeling of Dendrimer-Based siRNA Delivery Agents. Advances in Science and Technology, 2008, 57, 154-159
