Publications
Journals publications (*corresponding author(s))
1.Defang Ouyang, Hong Zhang, Harendra S. Parekh*, Sean C. Smith*.
The Effect of pH on PAMAM Dendrimer-siRNA Complexation - Endosomal Considerations as Determined by Molecular Dynamics Simulation.
Biophysical Chemistry. Accepted 6th June 2011.
2.Neha Shah, Raymond Steptoe*, Harendra S. Parekh*.
Low generation asymmetric dendrimers exhibit minimal toxicity and effectively complex DNA.
J. Pep. Sci., Feb 2011 (Epub).
3.Defang Ouyang, Hong Zhang, Harendra S. Parekh*, Sean C. Smith*.
Structure and Dynamics of Multiple Cationic Vectors-siRNA Complexation by All-Atomic Molecular Dynamics Simulations.
J. Phys. Chem. B, 2010, 114, 9231–9237.
4.Defang Ouyang, Hong Zhang, Dirk-Peter Herten, Harendra S. Parekh*, Sean C. Smith*.
Structure, Dynamics, and Energetics of siRNA-Cationic Vector Complexation: A Molecular Dynamics Study.
J. Phys. Chem. B, 2010, 114, 9220–9230.
5.Tathagata Dutta, Melinda Burgess, Nigel A.J. McMillan, Harendra S. Parekh*.
Dendrosome based delivery of siRNA against E6/E7 oncogenes in cervical cancer. Nanomedicine: Nanotechnology, Biology and Medicine 6, 2010, 463–470.
6.Defang Ouyang, Neha Shah, Hong Zhang, Sean C. Smith, Harendra S. Parekh*.
Reducible Disulfide-Based Non-Viral Gene Delivery Systems
Mini-Rev. Med. Chem., 2009, 9, 1242-1250.
7.Defang Ouyang, Hong Zhang, Dirk-Peter Herten, Harendra S. Parekh, Sean C. Smith*.
Flexibility of Short-Strand RNA in Aqueous Solution as Revealed by Molecular Dynamics Simulation: Are A-RNA and A-RNA Distinct Conformational Structures?
Aust. J. Chem. 2009, 62, 1054–1061.
8.S. Mutalik, A.K. Hewavitharana, P.N. Shaw, Y.G. Anissimov, M.S. Roberts, H.S. Parekh*.
Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments.
J. Chrom. B, 877, 2009, 3556–3562.
9.Harendra S Parekh*, Gang Liu and Ming Q Wei.
A new dawn for the use of traditional Chinese medicine in cancer therapy
Mol Cancer, 2009, 8, 21, 1-8.
10.S Mutalik*, H.S. Parekh, N.M. Davies, N Udupa.
A Combined Approach of Chemical Enhancers and Sonophoresis for the Transdermal Delivery of Tizanidine Hydrochloride. Drug Delivery, 2009, 16(2), 82-91.
11.H.S. Parekh*.
The Advance of Dendrimers – a versatile targeting platform for gene/drug delivery.
Curr Pharmaceutical Design, 2007, 13(27), 2837-2850.
12.H.S. Parekh*, R.J. Marano, P. E Rakoczy, J. Blanchfield, I. Toth.
Synthesis of a Library of Polycationic Lipid Core Dendrimers and their Evaluation in the Delivery of an Oligonucleotide with hVEGF Inhibition. Bioorg. Med. Chem., 2006, 14, 4775-4780.
Book Chapters
1.Book title: Nanotechnology in Health Care
Publisher: Shyam Prakashan, Jaipur, India
Chapter title: Introduction to Dendrimers – versatile vectors for drug and gene delivery
Chapter author: H.S. Parekh
Launch date: Dec 2010 (at Indian Pharmaceutical Congress meeting, Manipal University, India).
2.Book title: Nanotechnology in Health Care
Publisher: Shyam Prakashan, Jaipur, India
Chapter title: Dendrimers as carriers for the effective delivery of drugs and genes.
Chapter authors: Neha Shah, Defang, Ouyang, Srinivas Mutalik, H.S. Parekh
Launch date: Dec 2010 (at Indian Pharmaceutical Congress, Manipal University, India).
3.Book Title: Evidence-based Anticancer Herbal Medicine
Publisher: Springer-Verlag
Chapter title: An evidence-based perspective of herbal remedies for cancer patients
Chapter authors: H.S. Parekh, J. Jing
Launch date: Feb 2011.
